Mapping the Tau Cascade: New Insights from p-Tau 205 and p-Tau 212 for Disease Staging and Monitoring
NPTX2: A Synaptic Biomarker of Circuit Integrity, Cognitive Resilience, and Neurodegeneration
Neurology
Advancing Translational Neuroscience with the Simoa Mammalian GFAP Assay
Publication Brief Understanding astrocyte biology is essential for advancing translational neuroscience. GFAP has emerged as a leading biomarker of CNS injury, and Simoa® technology now enables its ultra-sensitive detection directly…
Proteomics in Transition: From Discovery to Diagnostic Relevance
Proteomics is moving beyond broad discovery to deliver real-time, clinically meaningful insights. At the forefront is Quanterix’s Simoa® digital immunoassay technology, enabling ultra-sensitive, reproducible detection of low-abundance biomarkers in areas…
Neurology
Beyond Blood: Expanding Simoa Applications in Urine, Saliva, Sweat, and Tears
Publication Brief The Quanterix Simoa® platform, known for ultrasensitive detection in plasma, serum, and CSF, now delivers the same performance in alternative matrices—urine, saliva, sweat, and tears. This publication brief…
Immunology
Simoa® IL-17A Advantage PLUS: Potential Biomarker Applications in Health and Disease
App Note IL-17A is a potent pro-inflammatory cytokine that plays critical roles in inflammatory responses, host defense against infections, and tissue regeneration. This application note delves into the physiological and…
Neurology
Beyond Blood: Tear Fluid as a Window into Biomarker Discovery
While blood and CSF have long dominated biomarker research, tear fluid is emerging as a scientifically relevant, non-invasive matrix for detecting systemic and neurological biomarkers. Produced by lacrimal glands and…
Neurology
Sweat As A Non-Invasive Matrix for Cytokine Detection Using Simoa®
Inflammatory cytokines like IL-6, IL-10, and TNF-α are central to understanding aging, immune dysregulation, and chronic disease. With eccrine glands distributed across the body, sweat offers a non-invasive, physiologically relevant…
Neurology
Expanding Access to Ultra-Sensitive Biomarker Testing: Urine as a Non-Invasive Matrix for Simoa Assays
Urine as a Non-Invasive Matrix for Ultra-Sensitive Biomarker Detection with Simoa® The Simoa® platform extends its unmatched sensitivity to urine, enabling detection of low-abundance neurological and infectious disease biomarkers in…
Neurology
Saliva as a Noninvasive Matrix for Immune Surveillance and Infectious Disease Research via Ultra-Sensitive Antibody Detection
Unlock Saliva’s Potential in Immune Monitoring Ultra-sensitive Simoa technology makes noninvasive, scalable, and high-fidelity immune profiling a reality. Immune monitoring has long depended on venous blood draws—accurate but limited by…
Neurology
Scientific Fact Sheet: p-Tau 212
p-Tau 212 Fact Sheet: A Key Blood-Based Biomarker for Early Alzheimer’s Detection Explore how p-Tau 212 is transforming Alzheimer’s disease research and diagnostics. As an early-to-mid stage biomarker, p-Tau 212…
Neurology
Scientific Fact Sheet: p-Tau 205
p-Tau 205 Fact Sheet: A Biomarker for Advanced Alzheimer’s Pathology Explore how p-Tau 205 offers unique insights into late-stage tau pathology. This quick-reference fact sheet highlights p-Tau 205’s role in…