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Diagnostic performance and prediction of clinical progression of plasma phospho-tau181 in the Alzheimer’s Disease Neuroimaging Initiative

Karikari et al.
Evidence supporting the use of plasma p-tau181 as a diagnostic and prognostic tool for Alzheimer’s disease continues to mount! This new study examined plasma p-tau181 performance in participants from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) and found that the biomarker demonstrated high diagnostic accuracy for AD and accurately predicted future dementia.

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Brain-Profile

Plasma N-terminal tau fragment levels predict future cognitive decline and neurodegeneration in healthy elderly individuals

Chhatwal et al.
Researchers found that plasma NT1 levels predicted future pathological tau accumulation, cognitive decline and neurodegeneration, suggesting that the marker may be indicative of early changes in the development of AD

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