Zhong et al.
The secretion of cytokines, including IL-6, IL-10 and TNF-α, is a key factor in embryo blastulation and implantation during IVF. Researchers measured these cytokines in single-blastocyst conditioned medium (SBCM) at specified time intervals. Results suggest that IL-6 was associated with embryo quality at specific points during blastulation but its role in implantation remained unclear. This study shows how ultrasensitive assays can lead to future advances in IVF through enhanced understanding of embryo development.
Immunology
App Note IL-17A is a potent pro-inflammatory cytokine that plays critical roles in inflammatory responses, host defense against infections, and tissue regeneration. This application note delves into the physiological and…
Immunology
Publication Brief Type 1 Interferons (IFNs) are a family of cytokines that play a central role in orchestrating the immune response to viral infections. Among them, IFN-α is the most…
Immunology
App Note IL-17A is a potent pro-inflammatory cytokine that plays critical roles in inflammatory responses, host defense against infections, and tissue regeneration. This application note delves into the physiological and…
Immunology
Publication Brief Advancing immuno-oncology research requires precise tools to measure key biomarkers like cytokines, which play a central role in the immune response to cancer therapies. Clinical responses to immunotherapies…
Immunology
Publication Brief Our understanding of neuroinflammation and its role in central nervous system (CNS) diseases has significantly advanced. Neuroinflammation is pivotal in both the acute response and long-term recovery from…
Immunology
App Note Cytokine levels measured in blood, especially in the chronic conditions, can be significantly influenced by inflammatory activities outside of the CNS. Conversely, peripheral inflammatory events can also impact…
Simoa, an ultra-sensitive immunoassay technology allows detection of proteins and nucleic acids at lowest possible levels.
