The UmanDiagnostics NF-light® test uses two highly specific non-competing monoclonal antibodies. One is immobilized on a solid phase and catches the neurofilament light (NF-L) in solution. The other antibody acts as detector which interacts with the bound protein and gives rise to a signal through biotin – horseradish peroxidase avidin binding. The signal obtained from the standard curve corresponds directly to the amount of NF-L.
Intended for research use only, not for use in diagnostic procedures, for detection of NF-L in human CSF. The kit contains material for 40 tests in duplicate.