MMP-9 (mouse)

Matrix metalloproteinase 9 (MMP-9) is a 92 kDa secreted protein, belonging to the metzincin (multi domain zinc (II) dependent endopeptidases) superfamily of proteases. It is produced by normal and transformed cells. MMP-9 functions through enzymatic degradation by cleaving extracellular matrix proteins and adhesion molecules (like ICAM-5). These events play major roles in the processes of synaptic plasticity, learning, memory, and morphological reconstruction of targets such as neuronal dendritic spines. MMP-9 has been shown to be linked to various disease states including cancer, cardiovascular disease and arthritis. Specifically, cancer models have shown directly that metastasis/angiogenesis and overall tumor aggression are linked to elevated MMP-9 levels.

Safety Data Sheets

The following Safety Data Sheets are associated with this Assay.

This website uses cookies. By continuing to use this website you are acknowledging and agree with our cookie policy.

AgreeLearn more