June 2021 Simoa® Publications: Alzheimer’s Disease

Effects of pre-analytical procedures on blood biomarkers for Alzheimer’s pathophysiology, glial activation, and neurodegeneration

Ashton NJ, et al.
Alzheimer’s & dementia (Amsterdam, Netherlands). 2021;13:e12168

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Lower White Matter Volume and Worse Executive Functioning Reflected in Higher Levels of Plasma GFAP among Older Adults with and Without Cognitive Impairment

Asken BM, et al.
J Int Neuropsychol Soc. 2021:1-12

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Longitudinal plasma phosphorylated tau 181 tracks disease progression in Alzheimer’s disease

Chen SD, et al.
Translational psychiatry. 2021;11:356

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Plasma biomarkers of Alzheimer’s disease improve prediction of cognitive decline in cognitively unimpaired elderly populations

Cullen NC, et al.
Nature communications. 2021;12:3555

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Detecting amyloid positivity in early Alzheimer’s disease using combinations of plasma Aβ42/Aβ40 and p-tau

Janelidze S, et al.
Alzheimer’s & dementia : the journal of the Alzheimer’s Association. 2021

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ADAMANT: a placebo-controlled randomized phase 2 study of AADvac1, an active immunotherapy against pathological tau in Alzheimer’s disease

Novak P, et al.
Nat Aging. 2021;1:521-534

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Prediction of future Alzheimer’s disease dementia using plasma phospho-tau combined with other accessible measures

Palmqvist S, et al.
Nat Med. 2021 Jun;27(6):1034-1042

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Plasma markers predict changes in amyloid, tau, atrophy and cognition in non-demented subjects

Pereira JB, et al.
Brain. 2021 Jun 2;awab163

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A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer’s disease

Salloway S, et al.
Nature medicine. 2021

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Development and validation of a high-sensitivity assay for measuring p217+tau in plasma

Triana-Baltzer G, et al.
Alzheimers Dement (Amst). 2021 May 27;13(1):e12204

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