January 2021 Simoa® Publications:

Infectious Disease, COVID-19 with Neurological Manifestations, Oncology, and Inflammation

Cerebrospinal fluid CXCL10 is associated with the presence of low level CSF HIV during suppressive antiretroviral therapy

Anderson AM, et al.
Journal of Neuroimmunology. 2021:577493.

HIV

Link to Article

Decreased Type I Interferon Production by Plasmacytoid Dendritic Cells Contributes to Severe Dengue

Upasani V, et al.
Frontiers in Immunology. 2020;11:605087.

Dengue

Link to Article

Serum neurofilament light chain levels in the intensive care unit: comparison between severely ill patients with and without COVID-19

Sutter R, et al.
Ann Neurol. 2021.

COVID-19 with Neurological Manifestations

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Biomarkers for CNS injury in CSF are elevated in COVID-19 and associated with neurological symptoms and disease severity

Virhammar J, et al.
European Journal of Neurology. 2021.

COVID-19 with Neurological Manifestations

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A phase 1b trial of the CXCR4 inhibitor mavorixafor and nivolumab in advanced renal cell carcinoma patients with no prior response to nivolumab monotherapy

Choueiri TK, et al.
Invest New Drugs (2021).

Oncology

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Clinical significance of circulating exosomal PD-L1 and soluble PD-L1 in extranodal NK/T-cell lymphoma, nasal-type

Li JW, et al.
Am J Cancer Res. 2021;10:4498-4512.

Oncology

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Constitutive Activation of Mitogen-activated Protein Kinase Kinase (MEK1) in Ileal Enterocytes Leads to Dysplasia and a Predisposition to Cancer

Shneider BL, et al.
Am J Physiol Gastrointest Liver Physiol. 2021

Oncology

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Differential Expression of Interferon-Alpha Protein Provides Clues to Tissue Specificity Across Type I Interferonopathies

Lodi L, et al.
J Clin Immunol. 2021.

Inflammation

Link to Article