Sweat As A Non-Invasive Matrix for Cytokine Detection Using Simoa® 

Inflammatory cytokines like IL-6, IL-10, and TNF-α are central to understanding aging, immune dysregulation, and chronic disease. With eccrine glands distributed across the body, sweat offers a non-invasive, physiologically relevant matrix for monitoring systemic inflammation.

Powered by the ultra-sensitive Simoa® platform, researchers can detect cytokines in sweat at femtomolar concentrations—overcoming the challenges of low-volume fluids and high-abundance protein interference seen in traditional matrices.

In this app note, you’ll learn how:

• Sweat cytokine profiles reflect age-related inflammatory trends
• Simoa enables precise detection in sweat with high sensitivity and reproducibility
• This matrix supports scalable, decentralized sampling in research and clinical settings

Download your copy of the application note and explore how sweat and Simoa^® are redefining the future of immune monitoring.