Resources by Therapeutic Area

Resources by Therapeutic Area

The goals of the present study using a novel assay for pTau were to examine and compare levels of plasma phospho-tau181 (pTau181) and plasma total tau by clinical diagnosis across the AD spectrum
The objective of the study was to investigate the association between sNfL and clinical and MRI measurements in a therapy-naive cohort of CIS and RRMS patients in the very early stage of disease.
Clostridium difficile infection (CDI) is a serious and sometimes life-threatening illness caused by toxin release from Clostridium difficile (CD), a gram-positive anaerobic bacterium. Infection with CD can cause clinical manifestations in a spectrum from asymptomatic carrier states to pseudomembrano…
Progressive cerebral accumulation of tau aggregates is a defining feature of Alzheimer’s disease (AD). A popular theory that seeks to explain the apparent spread of neurofibrillary tangle pathology proposes that aggregated tau is passed from neuron to neuron. Such a templated seeding process require…
 A blood-based biomarker of neuronal damage in sporadic Creutzfeldt-Jakob disease (sCJD) will be extremely valuable for both clinical practice and research aiming to develop effective therapies.