Publications & Posters
Single Molecule Arrays (Simoa) For The Ultra-sensitive Detection Of The Host Immune Response To Dengue Infection
Journal Of Clinical Microbiology | February 18, 2015
Shonda T. Gaylord, Sama Abdul-Aziz, David R. Walt
Journal of Clinical Microbiology, February 18, 2015
Dengue positive plasma was applied to an indirect single molecule array (Simoa) for the detection of anti-dengue IgG and IgM. The Simoas were 1,000 and 10,000 times more sensitive than ELISAs, respectively. Using Simoa, serology may be used for the detection of dengue infection in the acute phase.