HIV P24 Antigen Is Quantifiable At Low Concentrations In Human Cerebrospinal Fluid With Digital Elisa And Is Associated With Decreased Neuropsychological Performance
CLINICAL INFECTIOUS DISEASES
Albert Anderson, William Tyor, Mark Mulligan, Drenna Waldrop-Valverde, Jeffrey Lennox, Scott Letendre
Clinical Infectious Diseases
New tools are needed to understand HIV central nervous system involvement. In this brief report, we tested cerebrospinal fluid (CSF) samples from 15 study participants for p24 antigen using a high sensitivity assay. There was a strong correlation trend between CSF p24 concentration and worse neuropsychological performance.
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