Publications & Posters
Development Of A 4-Plex Digital Immunoassay For Detection Of Neurofilament-Light, TAU, Glial Fibrillary Acidic Protein And Ubiquitin C-Terminal Hydrolase L1 In Blood And Cerebrospinal Fluid.
AAIC 2017
Dandan Shan, Marcella Holdridge, Christina Raso, Lei Chang, David Wilson
Background:
Neurofilament Light Chain (NF-Light), Tau, Glia Fibrillary Acidic Protein (GFAP) and Ubiquitin c-Terminal Hydrolase L1 (UCH-L1) are emerging neurology biomarkers relevant for neurodegeneration and traumatic brain injury. Simultaneous measurement of NF-Light, Tau, GFAP and UCH-L1 in serum, plasma, and CSF in both healthy and diseased individuals is of great interest.