Uman Diagnostics NF-light™
UmanDiagnostics, a division of Quanterix, supplies Nf-Light™ antibodies and ELISA kits, which are widely recognized by researchers and biopharmaceutical and diagnostics companies world-wide as the premier solution for the detection of Nf-Light to advance the development of therapeutics and diagnostics for neurodegenerative conditions.
The UmanDiagnostics NF-light test uses two highly specific non-competing monoclonal antibodies. One is immobilized on a solid phase and catches the neurofilament light (NF- L) in solution. The other antibody acts as a detector which interacts with the bound protein and gives rise to a signal through biotin – horseradish peroxidase avidin binding. The signal obtained from the standard curve corresponds directly to the amount of NF-L.