G-CSF

G-CSF

Granulocyte Colony Stimulating Factor (G-CSF) is a 19.6 kDa glycoprotein which stimulates the growth of neutrophil granulocyte precursors at the myeloid progenitor cell level. Functionally, G-CSF is a cytokine and hormone produced by a number of different sources in the body which include monocytes, mesothelial cells, fibroblasts, and endothelial cells. An important clinical application of measuring G-CSF is in the treatment of transient phases of leukopenia following chemotherapy and/or radiotherapy. G-CSF can also act on neuronal cells as a neurotrophic factor. This property is currently under investigation for the development of treatment of neurological diseases such as cerebral ischemia.

Safety Data Sheets

The following Safety Data Sheets are associated with this Assay.