Product Brochures

Simoa® Phosphorylated-Tau 231 (p-Tau 231) Fact Sheet


Tau protein phosphorylated at threonine 231 (p-Tau231) is an important protein implicated in neurobiological processes, particularly within the context of neurodegenerative disorders. Characterized by a molecular weight of 48 kDa to 67 kDa, p-Tau 231 plays a pivotal role in the pathogenesis and progression of various neurodegenerative conditions. Within neuronal physiology, p-Tau 231 exhibits intricate associations with cellular structures, including microtubules, thereby influencing cytoskeletal dynamics and neuronal morphology. Through its phosphorylation at threonine 231, this protein undergoes conformational changes, impacting its ability to interact with other cellular components and consequently altering neuronal function. Download our fact sheet to learn more.