March 2021 Simoa® Publications:

Neurology: Alzheimer’s Disease, Stroke, and ALS

The validation status of blood biomarkers of amyloid and phospho-tau assessed with the 5-phase development framework for AD biomarkers

Ashton NJ, et al.
Eur J Nucl Med Mol Imaging (2021)

Alzheimer’s Disease

Link to Article

Astrogliosis and Episodic Memory in Late Life: Higher GFAP is Related to Worse Memory and White Matter Microstructure in Healthy Aging and Alzheimer’s Disease

Bettcher BM, et al.
Neurobiology of Aging. 2021

Alzheimer’s Disease

Link to Article

Blood Biomarkers to Differentiate Ischemic and Hemorrhagic Strokes Might Allow Prehospital Thrombolysis

Bustamante A, et al.
Neurology. 2021

Stroke

Link to Article

Plasma glial fibrillary acidic protein detects Alzheimer pathology and predicts future conversion to Alzheimer dementia in patients with mild cognitive impairment

Cicognola C, et al.
Alzheimers Res Ther. 2021;13:68

Alzheimer’s Disease

Link to Article

Plasma neurofilament light and phosphorylated tau 181 as biomarkers of Alzheimer’s disease pathology and clinical disease progression

Clark C, et al.
Alzheimers Res Ther. 2021;13:65

Alzheimer’s Disease

Link to Article

Ultrasensitive assays for detection of plasma tau and phosphorylated tau 181 in Alzheimer’s disease: a systematic review and meta-analysis

Ding X, et al.
Transl Neurodegener. 2021;10:10

Alzheimer’s Disease

Link to Article

Prediction of Outcome After Endovascular Embolectomy in Anterior Circulation Stroke Using Biomarkers

Pujol-Calderón F, et al.
Translational stroke research. 2021

Stroke

Link to Article

Ratio of urinary N-terminal titin fragment to urinary creatinine is a novel biomarker for amyotrophic lateral sclerosis

Yamada S, et al.
J Neurol Neurosurg Psychiatry. 2021 Mar 18;jnnp-2020-324615

ALS

Link to Article

March 2021 Simoa® Publications in Other Therapeutic Areas