- Home
- / Whitepapers
- / Advancing Alzheimer’s Disease Detection with p-Tau 205 and p-Tau 212
Advancing Alzheimer’s Disease Detection with p-Tau 205 and p-Tau 212
Posted on
Download the Publication BriefPublication Brief
As the Alzheimer’s disease (AD) research community accelerates efforts toward earlier diagnosis and more targeted therapeutic interventions, tau phosphorylation biomarkers have taken center stage for their potential to precisely map disease progression. Among these, site-specific phosphorylated tau species are now understood to represent distinct stages of tau pathobiology, from early seeding and conformational changes to mature neurofibrillary tangle accumulation. Recognizing this continuum, Quanterix has developed and launched two new ultrasensitive Simoa® assays: p-Tau 205 and p-Tau 212, which add critical granularity to the phosphorylated tau biomarker landscape.
Download our publication brief to learn more and to view a sampling of peer-reviewed research using Simoa® technology.
Share This Post
Related Posts
NPTX2: A Synaptic Biomarker of Circuit Integrity, Cognitive Resilience, and Neurodegeneration
Advancing Translational Neuroscience with the Simoa Mammalian GFAP Assay
Publication Brief Understanding astrocyte biology is essential for advancing translational neuroscience. GFAP has emerged as a leading biomarker of CNS injury, and Simoa® technology now enables its ultra-sensitive detection directly…
Proteomics in Transition: From Discovery to Diagnostic Relevance
Proteomics is moving beyond broad discovery to deliver real-time, clinically meaningful insights. At the forefront is Quanterix’s Simoa® digital immunoassay technology, enabling ultra-sensitive, reproducible detection of low-abundance biomarkers in areas…
Beyond Blood: Expanding Simoa Applications in Urine, Saliva, Sweat, and Tears
Publication Brief The Quanterix Simoa® platform, known for ultrasensitive detection in plasma, serum, and CSF, now delivers the same performance in alternative matrices—urine, saliva, sweat, and tears. This publication brief…
Simoa® IL-17A Advantage PLUS: Potential Biomarker Applications in Health and Disease
App Note IL-17A is a potent pro-inflammatory cytokine that plays critical roles in inflammatory responses, host defense against infections, and tissue regeneration. This application note delves into the physiological and…
Beyond Blood: Tear Fluid as a Window into Biomarker Discovery
While blood and CSF have long dominated biomarker research, tear fluid is emerging as a scientifically relevant, non-invasive matrix for detecting systemic and neurological biomarkers. Produced by lacrimal glands and…
Sweat As A Non-Invasive Matrix for Cytokine Detection Using Simoa®
Inflammatory cytokines like IL-6, IL-10, and TNF-α are central to understanding aging, immune dysregulation, and chronic disease. With eccrine glands distributed across the body, sweat offers a non-invasive, physiologically relevant…
Expanding Access to Ultra-Sensitive Biomarker Testing: Urine as a Non-Invasive Matrix for Simoa Assays
Urine as a Non-Invasive Matrix for Ultra-Sensitive Biomarker Detection with Simoa® The Simoa® platform extends its unmatched sensitivity to urine, enabling detection of low-abundance neurological and infectious disease biomarkers in…