December 2020 Simoa® Publications:

Alzheimer’s Disease and General Neurology

Amyloid-beta uptake by blood monocytes is reduced with ageing and Alzheimer’s disease

Chen SH, et al. Transl Psychiatry 10, 423 (2020).

Alzheimer’s Disease

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Individualized prognosis of cognitive decline and dementia in mild cognitive impairment based on plasma biomarker combinations

Cullen NC, et al. Nat Aging (2020).

Alzheimer’s Disease

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Comparison of ELISA- and SIMOA-based quantification of plasma Aβ ratios for early detection of cerebral amyloidosis

De Meyer S, et al. Alzheimers Res Ther. 2020;12:162.

Alzheimer’s Disease

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Head-to-head comparison of clinical performance of CSF phospho-tau T181 and T217 biomarkers for Alzheimer’s disease diagnosis

Karikari TK, et al. Alzheimers Dement. 2020 Nov 30.

Alzheimer’s Disease

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Blood-Based ATN Biomarkers of Alzheimer’s Disease: A Meta-Analysis

Koychev I, et al. J Alzheimers Dis. 2020 Nov 24.

Alzheimer’s Disease

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Time course of phosphorylated-tau181 in blood across the Alzheimer’s disease spectrum

Moscoso A, et al. Brain, awaa399.

Alzheimer’s Disease

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Full-length and C-terminal neurogranin in Alzheimer’s disease cerebrospinal fluid analyzed by novel ultrasensitive immunoassays

Öhrfelt A, et al. Alz Res Therapy 12, 168 (2020).

Alzheimer’s Disease

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Amyloid-β misfolding as a plasma biomarker indicates risk for future clinical Alzheimer’s disease in individuals with subjective cognitive decline

Stockmann J, et al. Alzheimers Res Ther. 2020;12:169.

Alzheimer’s Disease

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BACE inhibition causes rapid, regional, and non-progressive volume reduction in Alzheimer’s disease brain

Sur C, et al. Brain, awaa332.

Alzheimer’s Disease

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Head-to-head comparison of amplified plasmonic exosome Aβ42 platform and single-molecule array immunoassay in a memory clinic cohort

Tanaka T, et al. Eur J Neurol. 2020 Dec 28.

Alzheimer’s Disease

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Plasma neurofilament light chain as a potential biomarker in Charcot-Marie-Tooth disease

Millere E, et al. Eur J Neurol. 2020 Dec 19.

Neurology- General

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Serum biomarkers of cerebral cellular stress after self limited tonic clonic seizures: An exploratory study

Nass RD, et al. Seizure. 2020 Dec 17;85:1-5.

Neurology- General

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Neurofilament light plasma concentration positively associates with age and negatively associates with weight and height in the dog

Perino J, et al. Neurosci Lett. 2020 Dec 24;135593.

Neurology- General

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Plasma Total-Tau and Neurofilament Light Chain as Diagnostic Biomarkers of Alzheimer’s Disease Dementia and Mild Cognitive Impairment in Adults with Down Syndrome

Petersen ME, et al. Alzheimers Dis. 2020 Dec 16.

Neurology- General

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Mutant huntingtin and neurofilament light have distinct longitudinal dynamics in Huntington’s disease

Rodrigues FB, et al. Sci Transl Med. 2020 Dec 16;12(574):eabc2888.

Neurology- General

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