SIMOA® Bead

The technology to measure biomarkers at lower levels than ever before.

Quanterix’ digital biomarker detection technology, Simoa®, is changing the way in which the biology of health and disease is studied by giving researchers the ability to examine critical proteins and nucleic acids, at ultra low – even baseline – levels, in most common sample types.

Video about SIMOA Technology

We are on a mission to change the way in which healthcare is provided by giving researchers the ability to closely examine the continuum from health to disease. In our focused therapeutic areas, our revolutionary technology is helping researchers advance the science of precision health.

Detecting the Undetectable

Detecting the Undetectable

First of its kind detection capabilities

This innovative technology is perfectly suited for single- and multi-plex detection of key biomarkers at ultra-low levels in applications within all therapeutic areas, including oncology, neurology, cardiology, immunology, and infectious disease.

Detect biomarkers at femtogram levels

The innovative digital nature of the technique allows an average of 1000 times sensitivity increase over conventional assays, with CVs less than 10 percent.

See results in record time

Incubation time for analyte capture and detector binding is typically about 30 minutes, with five minutes for labeling by the streptavidin β-galactosidase (SBG) conjugate.

How It Works

Simoa, an ultra-sensitive immunoassay technology allows detection of proteins and nucleic acids at lowest possible levels.

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Aenean euismod bibendum laoreet. Proin gravida dolor sit amet lacus accumsan et viverra justo commodo. Proin sodales pulvinar sic tempor. Sociis natoque penatibus et magnis dis parturient montes, nascetur ridiculus mus. Nam fermentum, nulla luctus pharetra vulputate, felis tellus mollis orci, sed rhoncus pronin sapien nunc accuan eget.The sample is loaded into arrays, in the Simoa disc, consisting of more than 200,000 microwells – each large enough to hold one bead.

  • Paramagnetic particles coupled with antibodies designed to bind to specific targets are added to the sample.
  • Detection antibodies – capable of generating fluorescent product – are added.
  • The objective is to form an immunocomplex consisting of the bead, bound protein, and detection antibody.
  • At low concentrations, each bead will contain one bound protein, or none.
  • The sample is loaded into arrays, in the Simoa disc, consisting of more than 200,000 microwells – each large enough to hold one bead.

The Evolution of the Immunoassay

Revolutionizing new discoveries with ultra-sensitive detection.

Enable detection of thousands more targets for drug development, efficacy, and safety.

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SIMOA Bead Technology

Simoa means sensitivity. Find out how Quanterix’ Simoa Bead Technology is changing the way in which the biology of health and disease is studied.

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Planar Array Technology

With Simoa Senstivity™, Quanterix’ Planar Array Technology now gives researchers an incredibly simple, flexible, robust, and sensitive multiplex immunoassay platform for measuring biomarkers in most common sample types.

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