Simoa® Dry Blood Extraction Kit

Standardized Biomarker Extraction from Dried Blood and Plasma Spot Samples

The Simoa Dry Blood Extraction Kit enables scalable, reproducible analysis from dried plasma and blood spot (DPS/DBS) matrices. Designed for device-agnostic compatibility and analytical rigor, this solution supports decentralized sample collection without compromising on data quality. Engineered to maintain femtogram-level sensitivity and streamline pre-analytical steps, the Simoa Dry Blood Extraction Kit empowers researchers to overcome the limitations of sample handling logistics—unlocking new potential for longitudinal and multi-site studies.

Key Features of the Simoa Dry Blood Extraction Kit

  • Device-Agnostic Compatibility: Validated across multiple dried plasma and blood spot collection devices, our protocol ensures consistent biomarker recovery regardless of sampling platform. This flexibility enables robust data collection across decentralized or longitudinal research settings.
  • Harmonized, Semiautomated Workflow: Reduce pre-analytical variability with a standardized protocol that controls critical variables—including elution conditions, centrifugation, and buffer formulations. Achieve reproducible results across different sites, operators, and sample batches.
  • Preserves Analytical Sensitivity: Built to maintain the femtogram-level sensitivity of your downstream assays—including p-Tau 217 and future analytes—the extraction protocol protects critical signals for detecting low-abundance biomarkers in neurological, inflammatory, and systemic conditions.
  • Optimized for Downstream Simoa Assays: Fully compatible with Simoa® kits, the Simoa Dry Blood Extraction Kit fits seamlessly into existing workflows—no additional optimization required.

Built for the Way You Work

The Simoa Dry Blood Extraction Kit is designed to meet the diverse needs of researchers across neuroscience, clinical, and public health settings. For academic and translational neuroscience teams managing large cohorts or longitudinal studies, it offers a standardized, reproducible method for extracting biomarkers from small, remotely collected samples—helping reduce variability and improve data quality across sites. In pharmaceutical and biotech settings, where early-phase trials and decentralized study designs are becoming the norm, the kit provides a validated workflow that supports high-sensitivity biomarker detection, even with limited sample volumes. And for researchers operating in low-resource or global health environments, this solution enables reliable, lab-quality biomarker analysis from non-traditional sampling methods—eliminating logistical barriers without compromising scientific rigor.

Applications and Intended Use

The Simoa Dry Blood Extraction Kit provides the reagents necessary to extract analytes from capillary dry blood collection devices which enables the detection of low abundance analytes with Simoa assay kits. This extract kit is for research use only.

Kit Contents

Each extraction kit includes Quanterix extraction buffer and 2 precipitation plates. 

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