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Request Information on Neurology 4-Plex D (BD-Tau, NfL, GFAP*, UCH-L1*)

Key features of the Simoa® Neurology 4-Plex D Advantage PLUS Assay

  • First multiplex assay solution for simultaneous measurement of BD-Tau with NfL, GFAP*, and UCH-L1*
  • Ultra-sensitive quantification of 4 key neuro biomarkers at sub-picogram levels
  • Workflow efficiency with full automation enabled on the HD-X
  • Enhanced accuracy for longitudinal and large-scale studies powered by Advantage PLUS

Applications and Intended Use

Simoa® N4PD Advantage PLUS is a digital immunoassay for the quantitative determination of BD-Tau, NfL, BD-Tau, GFAP*, and UCH-L1* concentrations in human serum, EDTA plasma, and CSF samples.

Assay Specifications

  • Compatible instruments: HD-X
  • Analytical Lower Limit of Quantification (LLOQ): 0.259-3.48 pg/mL
  • Lower Limit of Detection (LOD): 0.029-0.577 pg/mL
  • Dynamic range: varies by marker and by sample type

(For detailed specifications, please refer to the N4PD Advantage PLUS Datasheet)

Kit Contents

The assay kit includes all necessary reagents and controls to perform 96 tests.

Related Resources

Uncover Insights with BD-Tau and Key Neurology Biomarkers

BD-Tau as a Plasma Biomarker of Neurodegeneration in Alzheimer’s Disease 

Unlocking the Potential of Serum Brain-Derived Tau as a Vital Biomarker in Severe Traumatic Brain Injury

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