Simoa PSD-95 Advantage PLUS Assay

Product number 104904

The Simoa® PSD-95 Advantage PLUS Assay measures postsynaptic density protein 95 (PSD-95), a key synaptic protein that provides critical insights into synaptic integrity. PSD-95 is an essential component of synaptic signaling complexes, playing a pivotal role in synaptic plasticity and cognitive function. Research has linked increased PSD-95 levels in cerebrospinal fluid (CSF) with neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD). As an emerging biomarker for synaptic degeneration, PSD-95 may also correlate with cognitive decline, offering valuable data for understanding disease progression and developing targeted treatments.

With subpicogram sensitivity, full automation on the HD-X, and lot-matched kits, the Simoa PSD-95 Advantage PLUS Assay provides reliable quantification of PSD-95 with a streamlined workflow, scalability, and consistency for research projects of all sizes.