Whitepapers & App Notes

Whitepapers & App Notes

March 21, 2019
The Simoa CorPlex Human Cytokine Panel 1 is a multiplex immunoassay for the quantitative measurement of 10 inflammatory biomarkers (IFNγ, IL-1β, IL-4, IL-5, IL-6, IL-8, IL-10, IL-12p70, IL-22, and TNFα) in serum and EDTA plasma on the Quanterix SP-X™ imaging and analysis platform.
February 27, 2019
Antibodies against an epitope conserved among species can be used to develop a single assay for multiple species. The Human Neurology 4-Plex “A” (N4PA) and Human Neurology 3-Plex “A” (N3PA) Simoa assay kits were evaluated for species cross-reactivity with mouse and rat samples.
January 04, 2019
Cell lysates can be prepared using a variety of methods including physical disruption, reagent-based lysis, or a combination. This document describes a novel Quanterix lysate diluent for running lysate samples with Simoa assays diluent.
December 20, 2018
In this Application Note, we demonstrate that the Simoa Neuro 4-Plex Assay can measure levels of three neuronal biomarkers – NF-Light (NfL), Tau, and GFAP – in normal, undiseased dried blood spots. DOWNLOAD THE APP NOTE
December 04, 2018
Here we describe a proof of concept assay to demonstrate use of the Simoa platform as a tool to measure levels of anti-drug antibodies (ADA) against Adalimumbab (Humira®). To compare performance, equivalent assays were run with the Simoa platform and a standard plate-based ELISA.
December 04, 2018
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December 04, 2018
Here we describe a proof of concept assay to demonstrate the Simoa platform as a tool for measuring concentration of the biotherapeutic drug IgG Adalimumbab (Humira®). A sandwich ELISA was created using anti-Adalimumbab antibodies as capture and detection.