Whitepapers & App Notes

Whitepapers & App Notes

April 25, 2019
Many immunoassays utilize the high affinity interaction of biotin and streptavidin as part of the immunocomplex built to measure the analyte of interest.
March 21, 2019
The Simoa CorPlex Human Cytokine Panel 1 is a multiplex immunoassay for the quantitative measurement of 10 inflammatory biomarkers (IFNγ, IL-1β, IL-4, IL-5, IL-6, IL-8, IL-10, IL-12p70, IL-22, and TNFα) in serum and EDTA plasma on the Quanterix SP-X™ imaging and analysis platform.
February 27, 2019
Antibodies against an epitope conserved among species can be used to develop a single assay for multiple species. The Human Neurology 4-Plex “A” (N4PA) and Human Neurology 3-Plex “A” (N3PA) Simoa assay kits were evaluated for species cross-reactivity with mouse and rat samples.
January 04, 2019
Cell lysates can be prepared using a variety of methods including physical disruption, reagent-based lysis, or a combination. This document describes a novel Quanterix lysate diluent for running lysate samples with Simoa assays diluent.
December 20, 2018
In this Application Note, we demonstrate that the Simoa Neuro 4-Plex Assay can measure levels of three neuronal biomarkers – NF-Light (NfL), Tau, and GFAP – in normal, undiseased dried blood spots. DOWNLOAD THE APP NOTE
December 04, 2018
Here we describe a proof of concept assay to demonstrate use of the Simoa platform as a tool to measure levels of anti-drug antibodies (ADA) against Adalimumbab (Humira®). To compare performance, equivalent assays were run with the Simoa platform and a standard plate-based ELISA.
December 04, 2018
Here we describe a proof of concept assay to demonstrate the Simoa platform as a tool for measuring concentration of the biotherapeutic drug IgG Adalimumbab (Humira®). A sandwich ELISA was created using anti-Adalimumbab antibodies as capture and detection.
December 04, 2018
DOWNLOAD THE APP NOTE