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Comparison Of Three Analytical Platforms For Quantification Of The Neurofilament Light Chain In Blood Samples: Elisa, Electrochemiluminescence Immunoassay And Simoa.

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Clinical Chemistry And Laboratory Medicine | April 12, 2016

Jens Kuhle et. al.
Clinical Chemistry and Laboratory Medicine
DOI: 10.1515/cclm-2015-1195

Background: Neuronal damage is the morphological substrate of persisting neurological disability. Neurofilaments (Nf) are specific cytoskeletal proteins of neurons and their quantification has shown encouraging results as a biomarker for axonal injury.