Publications & Posters
2014 AAPS, San Diego, CA
Michael Tanen, Russell Weiner, Omar Laterza Molecular Biomarkers & Diagnostics, Merck Research Laboratories, Rahway NJ 07065
Journal of Immunological Methods | May 14, 2015
We report a system and assay for performing fully-automated measurement of 6 proteins simultaneously with single molecule sensitivity.
Rapid, Fully Automated Digital Immunoassay for p24 Protein with the Sensitivity of Nucleic Acid Amplification for Detecting Acute HIV Infection
2015 American Association for Clinical Chemistry
Carlos Cabrera, Yao Chen, Lei Chang, David H. Wilson Quanterix Corporation, Lexington, MA
Plasma Concentration of the Neurofilament Light Protein (NFL) is a Biomarker of CNS Injury in HIV Infection: A Cross-Sectional Study
EBioMedicine | November 26, 2015
Cerebrospinal fluid (CSF) neurofilament light chain protein (NFL) is a sensitive marker of neuronal injury in a variety of neurodegenerative conditions, including the CNS dysfunction injury that is common in untreated HIV infection. However, an important limitation is the requirement for lumbar…
Analytical Chemistry | February 2, 2016
The cell is the basic unit of biology and protein expression drives cellular function. Tracking protein expression in single cells enables the study of cellular pathways and behavior, but requires methodologies sensitive enough to detect low numbers of protein molecules with a wide dynamic range to…
An ultrasensitive assay format for detecting ULK1 inhibition by monitoring the phosphorylation status of Atg13
Analytical Biochemistry | July 4, 2016
This study focuses on the inhibition of the autophagy initiating kinase ULK1 by measuring the both total Atg13 and the phosphorylation of Atg13(pSer318) from control and following compound treatment in either overexpressing or wild type tissue culture samples.