Publications & Posters
Journal of Neurotrauma | June 30, 2017
There is an urgent need to characterize the acute physiological effects of sport-related concussion (SRC). We investigated the effects of SRC on gray matter structure and diffusion metrics in collegiate athletes at 1.64 days (T1; n=33), 8.33 days (T2; n=30), and 32.15 days (T3; n=36) post-…
Development of Digital ELISAs for the Ultrasensitive Measurement of Serum Glial Fibrillary Acid Protein and Ubiquitin C-terminal Hydrolase L1 with Clinical Utility in Human Traumatic Brian Injury
Here we developed digital ELISA assays using single molecule array (Simoa) technology for ultrasensitive measurement of serum glial fibrillary acid protein (GFAP) and ubiquitin C-terminal hydrolase L1 (UCH-L1), respectively.
JCI Insight |August 17, 2017
Promising therapeutic approaches for eradicating HIV include transcriptional activation of provirus from latently infected cells using latency-reversing agents (LRAs) and immune-mediated clearance to purge reservoirs. Accurate detection of cells capable of producing viral antigens and virions, and…
2011 American Academy of Neurology Annual Meeting, Honolulu, Hawaii
D. Wilson1, E. Mortberg2, S. Rubertsson2, H. Zetterberg3, K. Blennow3, L. Song1, L. Chang1, G. Provuncher1, P. Patel1, E. Ferrell1, D. Fournier1, C. Kan1, T. Campbell1, A. Rivnak1, B. Pink1, K. Minnehan1, T. Piech1, D. Rissin1, D.
Ultra-sensitive protein detection using single molecule arrays (Simoa): the potential for detecting single molecules of botulinum toxin
The Botulinum | 2012
Single molecule arrays (Simoa) make it possible to detect subfemtomolar concentrations of proteins in complex samples. We describe the basis of Simoa and its potential application in the detection of proteins, such as botulinum neurotoxin (BoNT), from pathogenic bacteria. We also provide a concept…
Brain Injury | March 8, 2013
The aim of this study was to investigate if olympic (amateur) boxing is associated with elevation of brain injury biomarkers in peripheral blood compared to controls.