Publications & Posters - Technology

Publications & Posters - Technology

PLOS One | March 08, 2018
The three methods tested allow sensitive detection of GAD65, but SIMOA appears best suited for automated quantification of subpicomolar concentrations.
The Journal of Translational Immunology | February 12, 2018
The objective of this study was to examine the assay formats used to detect anti-drug antibodies (ADA) in clinical studies of the anti-TNF monoclonal antibodies adalimumab and infliximab in chronic inflammatory disease and their potential impact on pharmacokinetic and clinical outcomes.
Analytical Chemistry | February 09, 2018
This report describes a novel method for isolating and detecting individual enzyme molecules using polymer arrays of picoliter microwells.
February 03, 2018
Type 2 diabetes and obesity are pro-inflammatory states associated with increased risk of cardiovascular disease.
Analytica Chimica Acta | February 02, 2018
Human breath, along with urine and blood, has long been one of the three major biological media for assessing human health and environmental exposure.
ACS Sensors | January 24, 2018
Over the last decades, the study of cells, nucleic acid molecules, and proteins has evolved from ensemble measurements to so-called single-entity studies. The latter offers huge benefits, not only as biological research tools to examine heterogeneities among individual entities within a population…
American Journal of Clinical Pathology | January 11, 2018
The objective of this study was to clinically validate a new ultra-sensitive immunoassay platform with EDTA plasma patient specimens for eventual translation as a blood-based biomarker in immuno-oncology.
Molecular Immunology | January 08, 2018
Sensitivity of assays for detection of low abundance proteins have been improved by orders of magnitude based on unique properties of nanomaterials.
Molecular Immunology | January 08, 2018
Nanomaterials are beginning to play an important role in the next generation of immunological assays and biosensors, with potential impacts both in research and clinical practice. In this brief review, we highlight two areas in which nanomaterials are already making new and important contributions…
AAPS Journal | December 01, 2017
An in-depth evaluation of the Quanterix© Simoa™ platform was undertaken by scientists from the AAPS Emerging Technologies Focus Group to determine the overall performance of the technology as well as provide guidance to future users.