Publications & Posters
Journal of Neurology, Neurosurgery & Psychiatry | February 13, 2018
This study used an ultrasensitive single molecule methodology to measure plasma tau concentrations in 176 participants: 71 with bvFTD, 83 with PPA and 22 healthy controls.
Valproic Acid Treatment Decreases Serum GFAP and UCH‐L1 Levels in Swine Subjected to Traumatic Brain Injury
Journal of Neurotrauma | February 07, 2018
The primary aim of this study was to examine the effects of valproic acid (VPA) treatment on serum glial fibrillary acidic protein (GFAP) and neurofilament light chain (NF-L) levels.
HIV p24 antigen is quantifiable at low concentrations in human cerebrospinal fluid with digital ELISA and is associated with decreased neuropsychological performance
Clinical Infectious Diseases | January 29, 2018
In this brief report, we tested cerebrospinal fluid (CSF) samples from 15 study participants for p24 antigen using a high sensitivity assay.
Neurology | January 24, 2018
Neurofilament light (NfL) protein in blood plasma has been proposed as a prognostic biomarker of neurodegeneration in a number of conditions, including Huntington disease (HD). This study investigates the regional distribution of NfL-associated neural pathology in HD gene expansion carriers.
48 Single Molecule Array Ultra-Sensitive Cytokine Assays in EDTA Plasma Are Robust and Clinically Feasible
American Journal of Clinical Pathology | January 11, 2018
The objective of this study was to clinically validate a new ultra-sensitive immunoassay platform with EDTA plasma patient specimens for eventual translation as a blood-based biomarker in immuno-oncology.
Neurology | January 10, 2018
The objective of this study was to perform a cross-sectional study to determine whether plasma neurofilament light chain (NfL) concentration is elevated in patients with Charcot-Marie-Tooth disease (CMT) and if it correlates with disease severity.
Molecular Immunology | January 08, 2018
Sensitivity of assays for detection of low abundance proteins have been improved by orders of magnitude based on unique properties of nanomaterials.
Neurology | January 02, 2018
Study objective was to examine neurofilament (Nf) concentrations according to symptom onset and clinical diagnostic certainty categories of amyotrophic lateral sclerosis (ALS).
European Journal of Neurology | December 27, 2017
Serum Neurofilaments are markers of axonal injury. We addressed their diagnostic and prognostic role in acute ischemic stroke (AIS) and TIA.
Neurology | December 27, 2017
The study objective was to determine the ability of CSF biomarkers to predict disease progression in progressive supranuclear palsy (PSP).