Resources by Therapeutic Area
Ultrasensitive HIV-1 p24 detects single infected cells and differences in reservoir induction by latency-reversal agents
Journal of Virology | January 11, 2017
Here, we used an ultrasensitive p24 digital assay, which we report to be 1000 fold more sensitive than classical ELISA in the quantification of HIV-1 Gag p24 production in HIV-infected individuals samples.
Future Virology | December, 2016
In this review, we will discuss these methods highlighting the difficulties to accurately measure the LR, one main obstacle in curing HIV-1.
Rapid and ultrasensitive detection of botulinum neurotoxin serotype A1 in human serum and urine using single-molecule array method
Forensic Toxicology | September 2, 2016
Botulinum neurotoxin is one of the most poisonous substances ever known. It causes botulism, a persistent paralysis of peripheral nerve termini.
The Simoa p24 Antigen Assay is an ultra-sensitive digital immunoassay providing 1,000 times improvement in detection limits compared with a traditional ELISA. The method can be used to detect early reactivation of infectious virus from latent reservoirs and determine efficacy of drugs and therap
2016 Biomarkers & Diagnostics World Congress, Philadelphia, PA
Hepatitis B Virus (HBV) infection is still a serious global health problem and HBV infection is a leading cause of chronic hepatitis, liver cirrhosis and hepatocellular carcinoma.