The three methods tested allow sensitive detection of GAD65, but SIMOA appears best suited for automated quantification of subpicomolar concentrations.
Resources by Therapeutic Area
An analytical comparison of three immunoassay platforms for subpicomolar detection of protein biomarker GAD65.
New Research Demonstrates Enhanced Sensitivity for Acute HIV Detection Using Quanterix’ Simoa Technology
Research presented at Conference on Retroviruses and Opportunistic Infections (CROI) validates platform’s advanced detection capabilities and demonstrates potential to detect the infection at pre-symptomatic stages
February 15-16, 2018 | Manchester, UK
Visit us at booth #3
Immunoassay methods used in clinical studies for the detection of anti-drug antibodies to adalimumab and infliximab
The objective of this study was to examine the assay formats used to detect anti-drug antibodies (ADA) in clinical studies of the anti-TNF monoclonal antibodies adalimumab and infliximab in chronic inflammatory disease and their potential impact on pharmacokinetic and clinical outcomes.
This report describes a novel method for isolating and detecting individual enzyme molecules using polymer arrays of picoliter microwells.