Recombinant Human TGFβ2 is a 25.0 kDa protein composed two identical 112 amino acid polypeptide chains linked by a single disulfide bond. Human TGFβ exists as three isoforms (1,2,3), that are 70-80% homologous. As part of a Kinase complex, TGFβ initiates a signal cascade that upregulates target gene expression. Target genes activated by this cascade impact a wide range of functions including cell invasion, environmental modification, differentiation, proliferation, and immune cell activation. Modification of the normal TGFβ pathway is associated with cancer development. 


Safety Data Sheets

The following Safety Data Sheets are associated with this Assay.

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