PD-1 (planar)

Programmed cell death protein 1 (PD-1 or CD279) is a cell surface receptor that belongs to the immunoglobulin superfamily and is expressed on T cells, B cells, monocytes, and dendritic cells.  PD-1 plays an important role as an immune checkpoint. PD-1 binds to two ligands, PD-L1 and PD-L2. The PD-1/PD-L1 or PD-L2 signaling pathway is a negative regulatory mechanism that inhibits T cell proliferation and cytokine production. PD-1 inhibitors play a role in activation of the immune system and can be used for cancer treatment. Blockade of the PD-1/PD-L1 interaction enhances anti-tumor immunity and shows potential for improving cancer immunotherapy. The PD-1 pathway plays a major role in the inhibition of self-reactive T cells and protection against  autoimmune diseases.

Safety Data Sheets

The following Safety Data Sheets are associated with this Assay.

This website uses cookies. By continuing to use this website you are acknowledging and agree with our cookie policy.

AgreeLearn more