Matrix metalloproteinase-3

Matrix metalloproteinase-3 (MMP-3), also known as Stromelysin-1, is a matrix metalloproteinase enzyme involved in the breakdown of extracellular matrix proteins and tissue remodeling. The MMP-3 enzyme degrades collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin, and can activate other MMPs such as MMP-1, MMP-7, and MMP-9. MMP-3 has been implicated in exacerbating the effects of traumatic brain injury (TBI) through its disruption of the blood-brain barrier, and is also thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation.

Safety Data Sheets

The following Safety Data Sheets are associated with this Assay.

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