IL-1α

Interleukin 1 alpha

Interleukin 1 alpha (IL-1α), a pro-inflammatory cytokine of 271 amino acids, is mainly produced by activated macrophages, as well as neutrophils, epithelial cells, and endothelial cells. Both the 31 kDa precursor form of IL-1α and its 18 kDa mature form are biologically active. The IL-1α precursor is released upon cell death as occurs in ischemic diseases such as myocardial infarction, stroke, acute renal failure, and tumor necrosis. IL-1α, mediator of inflammatory reactions, is produced in minute quantities and is active in very low concentrations in serum and plasma.

Safety Data Sheets

The following Safety Data Sheets are associated with this Assay.