ICAM-1 (mouse)

Intercellular adhesion molecule-1 (ICAM-1; also known as CD54) is a 90kDa member of the immunoglobulin (Ig) superfamily and plays a central role in leukocyte trafficking, activation of ymphocytes, and numerous additional immune functions. ICAM-1 is constitutively expressed on many immune, endothelial and epithelial cell types, and its expression is upregulated in inflammatory conditions, specifically by TNF-α, IL-1β, IFN-γ and other cytokines. By interacting with lymphocyte function associated molecule (LFA)-1 and others, ICAM-1 acts as a leukocyte adhesion molecule. ICAM-1 is highly expressed in inflammatory conditions, chronic diseases and a number of malignancies.

Safety Data Sheets

The following Safety Data Sheets are associated with this Assay.

This website uses cookies. By continuing to use this website you are acknowledging and agree with our cookie policy.

AgreeLearn more