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Assay Able To Detect Neuron Damage In Blood May Serve As Early Ms Diagnostic Tool


Quanterix and UmanDiagnostics are working to advance an assay capable of detecting neuron damage in a blood sample — a tool that could aid in the early diagnosis of multiple sclerosis (MS) and other neurodegenerative conditions.

The collaboration brings Quanterix’ Simoa technology together with Uman’s antibodies against neurofilament light (Nf-L) — a marker of nerve cell degeneration. In early disease stages, the factor is found in extremely low concentrations in the blood, a reason it hasn’t been used until now. The assay is ultrasensitive, Quanterix reported, and able to get around that problem.