Healio | September 6, 2023
Compared with absolute values, serum neurofilament light chain Z scores were linked to higher effect size metrics and more accurate estimation of persistent neuroaxonal damage in pediatric populations, per data from The Lancet Neurology.
Lead study author Ahmed Abdelhak, MD, of the Weill Institute for Neurosciences at the University of California, San Francisco, and colleagues sought to create an age-adjusted serum neurofilament light (sNfL) reference range database for healthy children and adolescents, as well as to find validation for it by examining two additional cohorts of pediatric patients with a range of neurological conditions.
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