Measuring inflammatory markers
in normal and disease samples

Simoa assays can measure inflammatory and anti-inflammatory molecules in serum and plasma with unprecedented sensitivity enabling new discoveries into the role of inflammation in the biology of health and disease.

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This study investigated the capability of the Quanterix Simoa HD-1 to measure interleukin (IL)-5 , - 13, and -17A in serum samples to determine if increasing assay sensitivity will allow us to convincingly detect these cytokines at baseline.
Four bioanalytical platforms were evaluated to optimize sensitivity and enable detection of recombinant human GDF11 in biological matrices. Simoa achieved the greatest sensitivity, an improvement of 100-fold over the next sensitive platform.

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